Having a high IQ reduces mental distress even in those with high levels of inflammation, a study found.
Previous research links inflammation with a higher risk of the mental-health disorder.
Study author Professor Eirini Flouri, from University College London, said: 'There appears to be some protective effect of having a high IQ.'
This may be due to intelligent people being more likely to lead healthy lifestyles, such as eating well and exercising regularly, according to the researchers.
The study also found intelligence does not protect women from depression, which may be due to hormonal or immune-system differences between the sexes, they add.
Experts believe men can boost their intelligence, and therefore reduce their risk of the mental-health condition, by doing activities that improve their memories.
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